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Drug Name | PX-866 |
Trade Name | |
Synonyms | Sonolisib|PX866 |
Drug Descriptions |
Sonolisib (PX-866) is a PI3K inhibitor, which inhibits the activation of the PI3K/Akt signaling pathway, thereby inhibiting cancer cell motility and growth (PMID: 17766839). |
DrugClasses | PI3K Inhibitor (Pan) 41 |
CAS Registry Number | 502632-66-8 |
NCIT ID | C78848 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Abiraterone + PX-866 | Abiraterone PX-866 | 0 | 0 |
PX-866 | PX-866 | 3 | 0 |
PX-866 + Sorafenib | PX-866 Sorafenib | 0 | 0 |
PX-866 + Vemurafenib | PX-866 Vemurafenib | 1 | 0 |