Drug Detail


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Drug Name PX-866
Trade Name
Synonyms Sonolisib|PX866
Drug Descriptions

Sonolisib (PX-866) is a PI3K inhibitor, which inhibits the activation of the PI3K/Akt signaling pathway, thereby inhibiting cancer cell motility and growth (PMID: 17766839).

DrugClasses PI3K Inhibitor (Pan) 40
CAS Registry Number 502632-66-8
NCIT ID C78848


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abiraterone + PX-866 Abiraterone PX-866 0 0
PX-866 PX-866 3 0
PX-866 + Sorafenib PX-866 Sorafenib 0 0
PX-866 + Vemurafenib PX-866 Vemurafenib 1 0

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