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Drug Name GSK343
Trade Name
Synonyms GSK-343|GSK 343
Drug Descriptions

GSK343 is an inhibitor of EZH2, which decreases tri-methylation of H3K27, potentially resulting in decreased growth and increased apoptosis of tumor cells (PMID: 23759589, PMID: 31791385).

DrugClasses EZH2 inhibitor 20
CAS Registry Number 1346704-33-3
NCIT ID NA

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Dasatinib + GSK343 Dasatinib GSK343 0 0
GSK343 GSK343 0 0
GSK343 + MK2206 GSK343 MK2206 0 0
GSK343 + Selumetinib GSK343 Selumetinib 0 0


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