Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name GSK2256098
Trade Name
Synonyms GSK-2256098|GSK 2256098
Drug Descriptions

GSK2256098 is an inhibitor of focal adhesion kinase (FAK), which blocks integrin signaling and therefore, has antitumor activities (PMID: 21787277, PMID: 30992546).

DrugClasses FAK inhibitor 15
CAS Registry Number 1224887-10-8
NCIT ID C88346


  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")


  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Cisplatin + GSK2256098 Cisplatin GSK2256098 0 0
GSK2256098 GSK2256098 2 1
GSK2256098 + Paclitaxel GSK2256098 Paclitaxel 1 0
GSK2256098 + Topotecan GSK2256098 Topotecan 1 0
GSK2256098 + Trametinib GSK2256098 Trametinib 0 1

Additional content available in CKB BOOST