Drug Detail


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Drug Name AZD5153
Trade Name
Synonyms AZD-5153
Drug Descriptions

AZD5153 is a selective BET inhibitor that binds to BRD4 bivalently, resulting in enhanced anti-tumor activity (PMID: 27573426, PMID: 31392631).

DrugClasses BRD4 Inhibitor 10
CAS Registry Number 1869912-39-9
NCIT ID C151943


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Therapy Name Drugs Efficacy Evidence Clinical Trials
AZD5153 AZD5153 1 1
AZD5153 + Durvalumab AZD5153 Durvalumab 0 0
AZD5153 + Durvalumab + Selumetinib AZD5153 Durvalumab Selumetinib 0 1
AZD5153 + Olaparib AZD5153 Olaparib 0 0
AZD5153 + Selumetinib AZD5153 Selumetinib 0 1

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