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Drug Name LOXO-195
Trade Name
Synonyms BAY 2731954|Selitrectinib
Drug Descriptions

LOXO-195 is an inhibitor of NTRK1, NTRK2, and NTRK3, which may result in inhibition of tumor growth and tumor regression (PMID: 28578312).

DrugClasses Trk Receptor Inhibitor (Pan) 23

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Crizotinib + LOXO-195 Crizotinib LOXO-195 0 0
Dabrafenib + LOXO-195 + Trametinib Dabrafenib LOXO-195 Trametinib 0 0
LOXO-195 LOXO-195 1 1
LOXO-195 + Trametinib LOXO-195 Trametinib 0 0


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