Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name XmAb20717
Trade Name
Synonyms XmAb 20717|Vudalimab
Drug Descriptions

XmAb20717 (Vudalimab) is a bispecific antibody that targets both PD-1 (PDCD1) and CTLA4, potentially resulting in increased anti-tumor immune response (Journal for ImmunoTherapy of Cancer 2021;9).

DrugClasses CTLA4 Antibody 29 Immune Checkpoint Inhibitor 147 PD-L1/PD-1 antibody 117
CAS Registry Number 2329669-72-7
NCIT ID C150463

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Abiraterone + Docetaxel + XmAb20717 Abiraterone Docetaxel XmAb20717 0 1
Abiraterone + XmAb20717 Abiraterone XmAb20717 0 1
Cabazitaxel + Carboplatin + XmAb20717 Cabazitaxel Carboplatin XmAb20717 0 1
Enzalutamide + XmAb20717 Enzalutamide XmAb20717 0 1
Olaparib + XmAb20717 Olaparib XmAb20717 0 1
Regorafenib + XmAb20717 Regorafenib XmAb20717 0 1
XmAb20717 XmAb20717 0 6


Additional content available in CKB BOOST