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Drug Name | IMG-7289 |
Trade Name | |
Synonyms | IMG7289|IMG 7289|Bomedemstat |
Drug Descriptions |
IMG-7289 irreversibly inhibits lysine-specific demethylase 1 (KDM1A, LSD1), resulting in growth inhibition of hematopoietic cells (PMID: 29453291, PMID: 31801559). |
DrugClasses | KDM1A Inhibitor 15 |
CAS Registry Number | 1990504-34-1 |
NCIT ID | C131827 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Atezolizumab + IMG-7289 | Atezolizumab IMG-7289 | 0 | 1 |
IMG-7289 | IMG-7289 | 3 | 5 |
IMG-7289 + Ruxolitinib | IMG-7289 Ruxolitinib | 2 | 0 |
IMG-7289 + Venetoclax | IMG-7289 Venetoclax | 0 | 1 |