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Drug Name IMG-7289
Trade Name
Synonyms IMG7289|IMG 7289|Bomedemstat
Drug Descriptions

IMG-7289 irreversibly inhibits lysine-specific demethylase 1 (KDM1A, LSD1), resulting in growth inhibition of hematopoietic cells (PMID: 29453291, PMID: 31801559).

DrugClasses KDM1A Inhibitor 15
CAS Registry Number 1990504-34-1
NCIT ID C131827


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + IMG-7289 Atezolizumab IMG-7289 0 1
IMG-7289 IMG-7289 3 3
IMG-7289 + Ruxolitinib IMG-7289 Ruxolitinib 2 0
IMG-7289 + Venetoclax IMG-7289 Venetoclax 0 1

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