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Drug Name KHK2455
Trade Name
Synonyms KHK-2455|KHK 2455
Drug Descriptions

KHK2455 is an IDO1 inhibitor, which results in reduced levels of kynurenine, leading to immune cell activation and subsequent tumor growth inhibition of cancer cells expressing IDO-1 (NCI Drug Dictionary).

DrugClasses IDO1 Inhibitor 10 Immune Checkpoint Inhibitor 98
CAS Registry Number NA
NCIT ID C129790

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Avelumab + KHK2455 Avelumab KHK2455 0 1
KHK2455 KHK2455 0 0
KHK2455 + Mogamulizumab KHK2455 Mogamulizumab 1 1


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