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Drug Name BI 1701963
Trade Name
Synonyms BI1701963|BI-1701963
Drug Descriptions

BI 1701963 binds to SOS1 thus prevents SOS1 interaction with Kras-GDP, resulting in inhibition of Kras downstream signaling and potential inhibition of tumor cell growth (AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, Oct 2019, Abstract PL06-01).

DrugClasses KRAS Inhibitor 6

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Therapy Name Drugs Efficacy Evidence Clinical Trials
BI 1701963 BI 1701963 0 1
BI 1701963 + Trametinib BI 1701963 Trametinib 0 1


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