Drug Detail


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Drug Name Minnelide
Trade Name
Drug Descriptions

Minnelide is a water-soluble prodrug of the naturally derived diterpene triepoxide, triptolide, which induces apoptosis and inhibits cell proliferation, leading to reduced tumor growth (PMID: 28192510, PMID: 32733649).



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Therapy Name Drugs Efficacy Evidence Clinical Trials
Irinotecan + Minnelide Irinotecan Minnelide 1 0
Minnelide Minnelide 1 1
Minnelide + Plicamycin Minnelide Plicamycin 0 0

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