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Therapy Name | PHA-533533 |
Synonyms | |
Therapy Description |
PHA-533533 is an inhibitor of CDK1, CDK2, CDK4, CDK5, and GSK3B, which inhibits phosphorylation of downstream targets and may promote cell cycle arrest and apoptosis in cancer cells (PMID: 15828833, PMID: 24004674). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
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PHA-533533 | CDK1 Inhibitor 13 CDK2 Inhibitor 30 CDK4 Inhibitor 17 CDK5 Inhibitor 8 GSK-3beta Inhibitor 4 | PHA-533533 is an inhibitor of CDK1, CDK2, CDK4, CDK5, and GSK3B, which inhibits phosphorylation of downstream targets and may promote cell cycle arrest and apoptosis in cancer cells (PMID: 15828833, PMID: 24004674). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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