Disease Detail

ID DOID:1037
Name lymphocytic leukemia
Definition A leukemia that has_material_basis_in lymphoblasts (immature white blood cells).
Source DiseaseOntology.org
Alt Ids DOID:10747
Path disease disease of cellular proliferation cancer organ system cancer hematologic cancer leukemia lymphocytic leukemia

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
ATM inact mut Olaparib lymphocytic leukemia sensitive detail...
Unknown unknown Ponatinib lymphocytic leukemia not applicable detail...
Clinical Trial Phase Therapies Title Recruitment Status
NCT00990249 Phase II anti-thymocyte globulin + Busulfan + Clofarabine Busulfan Plus Clofarabine Followed by Allogeneic Hematopoietic Stem Cell Transplantation Completed
NCT01319981 Phase II Pegfilgrastim Imatinib Filgrastim Rituximab Doxorubicin Dexamethasone Vincristine Cyclophosphamide Hyper-CVAD With Liposomal Vincristine in Acute Lymphoblastic Leukemia Active, not recruiting
NCT02116777 Phase Ib/II Talazoparib + Temozolomide BMN-673 and Temozolomide in Treating Younger Patients With Refractory or Recurrent Malignancies Completed
NCT02512497 Phase I Romidepsin Busulfan + Fludarabine + Romidepsin Romidepsin Maintenance After Allogeneic Stem Cell Transplantation Recruiting
NCT02535806 Phase II Vincristine Bortezomib Pegaspargase Methotrexate Cytarabine Mitoxantrone Prednisone Four Drug Reinduction With Bortezomib for Relapsed or Refractory ALL or LL in Children and Young Adults Terminated
NCT03136146 Phase II Cyclophosphamide Bortezomib Etoposide Rituximab Ofatumumab Clofarabine Pegfilgrastim Study of Clofarabine, Etoposide, Cyclophosphamide [CEC], Liposomal Vincristine (VCR), Dexamethasone and Bortezomib in Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) and Lymphoblastic Lymphoma (LL) Recruiting
NCT03792256 Phase I Cytarabine + Hydrocortisone + Methotrexate Cytarabine + Doxorubicin + Palbociclib + Pegaspargase + Prednisone + Vincristine Methotrexate Cytarabine + Doxorubicin + Palbociclib + Pegaspargase + Prednisolone + Vincristine Palbociclib in Combination With Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LL) Recruiting