Disease Detail

ID DOID:1816
Name angiosarcoma
Definition A vascular cancer that derives_from the cells that line the walls of blood vessels or lymphatic vessels.
Source DiseaseOntology.org
Alt Ids DOID:4508 DOID:267
Path disease disease of cellular proliferation cancer organ system cancer cardiovascular cancer vascular cancer angiosarcoma

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
Unknown unknown Bevacizumab + Paclitaxel angiosarcoma not applicable detail...
Unknown unknown Carotuximab + Pazopanib angiosarcoma not applicable detail...
Unknown unknown Alisertib angiosarcoma not applicable detail...
Clinical Trial Phase Therapies Title Recruitment Status
NCT01396408 Phase II Temsirolimus Sunitinib A Phase II Study of Sunitinib or Temsirolimus in Patients With Advanced Rare Tumours Active, not recruiting
NCT01446809 Phase I Doxorubicin + Ifosfamide Doxorubicin + Ifosfamide + Pazopanib Pazopanib Hydrochloride Followed By Chemotherapy and Surgery in Treating Patients With Soft Tissue Sarcoma Completed
NCT01462630 Phase II Pazopanib Pazopanib Hydrochloride in Treating Patients With Advanced Angiosarcoma Recruiting
NCT02048722 Phase II Regorafenib Daily Oral Regorafenib for Chemotherapy-Refractory, Metastatic and Locally Advanced Angiosarcoma Recruiting
NCT02584309 Phase II Dexrazoxane Doxorubicin + Olaratumab Doxorubicin With Upfront Dexrazoxane Plus Olaratumab for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma Recruiting
NCT02815995 Phase II Durvalumab + Tremelimumab Multi-Arm Study to Test the Efficacy of Immunotherapeutic Agents in Multiple Sarcoma Subtypes Active, not recruiting
NCT02979899 Phase III Pazopanib Carotuximab + Pazopanib A RANDOMIZED PHASE 3 TRIAL OF TRC105 AND PAZOPANIB VERSUS PAZOPANIB ALONE IN PATIENTS WITH ADVANCED ANGIOSARCOMA (TAPPAS) Active, not recruiting
NCT02987959 Phase II Sapanisertib Study of TAK-228 (MLN0128) in Soft Tissue Sarcomas Recruiting
NCT03009201 Phase I Doxorubicin + Ribociclib Ribociclib and Doxorubicin Hydrochloride in Treating Patients Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery Recruiting
NCT03282344 Phase II Nivolumab + NKTR-214 A Study of NKTR-214 in Combination With Nivolumab in Patients With Metastatic and/or Locally Advanced Sarcoma Recruiting