Disease Detail


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ID DOID:4866
Name salivary gland adenoid cystic carcinoma
Definition A salivary gland carcinoma that is characterized by a distinctive pattern in which abnormal nests or cords of epithelial cells surround and/or infiltrate ducts or glandular structures within the affected organ. These structures are typically filled with a mucous-like material or contain abnormal fibrous membranes.
Source DiseaseOntology.org
Alt Ids
Path disease disease of cellular proliferation cancer organ system cancer gastrointestinal system cancer oral cavity cancer salivary gland cancer salivary gland carcinoma salivary gland adenoid cystic carcinoma


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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
TP53 wild-type SAR405838 salivary gland adenoid cystic carcinoma predicted - sensitive detail...
FGFR1 positive Rogaratinib salivary gland adenoid cystic carcinoma predicted - sensitive detail...
TP53 wild-type Cisplatin + SAR405838 salivary gland adenoid cystic carcinoma predicted - sensitive detail...
ATM P1069fs ATM LOH Ceralasertib + Olaparib salivary gland adenoid cystic carcinoma predicted - sensitive detail...
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT01678105 Phase II Dovitinib A Phase II Study of Dovitinib in Recurrent and/or Metastatic Adenoid Cystic Carcinoma of the Salivary Glands (DOVE) Completed CAN 0
NCT03146650 Phase II Ipilimumab + Nivolumab Nivolumab and Ipilimumab in Treating Patients With Metastatic Recurrent Major or Minor Salivary Gland Cancer Unknown status USA 0
NCT05010629 Phase II 9-ING-41 + Carboplatin 9-ING-41 Plus Carboplatin in Salivary Gland Carcinoma Recruiting USA 0