Disease Detail


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ID DOID:80876
Name IDH-wildtype anaplastic astrocytoma
Definition An anaplastic astrocytoma lacking mutations in IDH1 or IDH2 genes.
Source DiseaseOntology.org
Alt Ids
Path disease disease of cellular proliferation cancer cell type cancer high grade glioma malignant astrocytoma anaplastic astrocytoma IDH-wildtype anaplastic astrocytoma


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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05120960 Phase I Tepotinib Osimertinib + Tepotinib A Phase 1a/1b Study to Determine the Recommended Phase 2 Dose, of Tepotinib in Participants With MET Alterations and Brain Tumors Withdrawn 0
NCT05271240 Phase III Bevacizumab + Temozolomide Temozolomide Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM Recruiting USA 0
NCT05938387 Phase I CVGBM Safety and Tolerability of CVGBM in Adults With Newly Diagnosed MGMT-Unmethylated Glioblastoma or Astrocytoma Active, not recruiting NLD | DEU | BEL 0