Drug Detail

Drug Name RXDX-105
Trade Name
Synonyms AC013773|CEP-32496
Drug Descriptions

RXDX-105 (CEP-32496) inhibits wild-type BRAF, BRAF V600E, c-RAF, ABL1 (and BCR-ABL), c-KIT, RET, PDGFR beta, and VEGFR2, potentially resulting in decreased tumor growth (PMID: 22319199).

DrugClasses ABL Inhibitor (pan) 8 ABL1 Inhibitor 5 BCR-ABL Inhibitor 24 BRAF Inhibitor 19 CRAF Inhibitor 11 KIT Inhibitor 50 PDGFR-beta Inhibitor 13 RET Inhibitor 36 VEGFR2 Inhibitor 34

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Therapy Name Drugs Efficacy Evidence Clinical Trials
RXDX-105 RXDX-105 8 3


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