Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name LY294002
Trade Name
Synonyms LY-294002|LY 294002|NSC-697286|SF-1101
Drug Descriptions

LY294002 is a specific inhibitor of PI3K alpha, beta, and delta, which leads to inhibition of PI3K-Akt/PKB signaling (PMID: 12060641, PMID: 31759362, PMID: 31732769).

DrugClasses PI3K Inhibitor (Pan) 38
CAS Registry Number 154447-36-6
NCIT ID C148229

Filtering

  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"

Sorting

  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Cisplatin + LY294002 Cisplatin LY294002 1 0
E6201 + LY294002 E6201 LY294002 1 0
Gefitinib + LY294002 Gefitinib LY294002 0 0
Imatinib + LY294002 Imatinib LY294002 0 0
LY294002 LY294002 1 0
LY294002 + RU-SKI 43 LY294002 RU-SKI 43 0 0
LY294002 + Sirolimus LY294002 Sirolimus 0 0


Additional content available in CKB BOOST