Drug Detail


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Drug Name Asciminib
Trade Name
Synonyms ABL001|ABL-001
Drug Descriptions

Asciminib (ABL001) is an allosteric inhibitor of BCR-ABL that binds to a unique location outside the ATP binding site, resulting in decreased BCR-ABL kinase activity and reduced tumor growth (Blood Dec 2014, 124 (21) 398, PMID: 31543464, PMID: 31826340).

DrugClasses BCR-ABL Inhibitor 27
CAS Registry Number 1492952-76-7
NCIT ID C114494


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Asciminib Asciminib 0 3
Asciminib + Dasatinib Asciminib Dasatinib 0 1
Asciminib + Dasatinib + Prednisone Asciminib Dasatinib Prednisone 0 1
Asciminib + Imatinib Asciminib Imatinib 0 2
Asciminib + Nilotinib Asciminib Nilotinib 0 1
Asciminib + Ponatinib Asciminib Ponatinib 0 0

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