Drug Detail


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Drug Name Mocetinostat
Trade Name
Synonyms MGCD0103|MG-0103
Drug Descriptions

Mocetinostat (MGCD0103) selectively inhibits Class I histone-deacetelyases (HDACs), which may result in increased tumor cell death (PMID: 21317455, PMID: 20538840, PMID: 31534435).

DrugClasses HDAC Inhibitor 45
CAS Registry Number 726169-73-9
NCIT ID C62521


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Brentuximab vedotin + Mocetinostat Brentuximab vedotin Mocetinostat 0 1
Cytarabine + Mocetinostat Cytarabine Mocetinostat 1 0
Durvalumab + Mocetinostat Durvalumab Mocetinostat 0 2
Gemcitabine + Mocetinostat Gemcitabine Mocetinostat 0 1
Guadecitabine + Mocetinostat + Pembrolizumab Guadecitabine Mocetinostat Pembrolizumab 0 1
Ipilimumab + Mocetinostat + Nivolumab Ipilimumab Mocetinostat Nivolumab 0 1
Mocetinostat Mocetinostat 0 2
Mocetinostat + Nivolumab Mocetinostat Nivolumab 0 1
Mocetinostat + Trametinib Mocetinostat Trametinib 1 0
Mocetinostat + Vinorelbine Mocetinostat Vinorelbine 0 1

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