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Qinlock (ripretinib) is a dual inhibitor of KIT and PDGFRa, resulting in growth inhibition and anti-tumor effects (PMID: 29439183, PMID: 31085175, PMID: 31201392). Qinlock (ripretinib) is FDA approved for use in patients with advanced gastrointestinal stromal tumor who received 3 or more prior kinase inhibitor therapies (FDA.gov)
|DrugClasses||KIT Inhibitor 51 PDGFR-alpha Inhibitor 9|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|