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Drug Name LY3295668
Trade Name
Synonyms LY3295668 erbumine|AK-01
Drug Descriptions

LY3295668 selectively inhibits Aurora A kinase (AURA), which results in apoptosis, inhibition of cell proliferation, and tumor growth inhibition (PMID: 31530649).

DrugClasses Aurka Inhibitors 24
CAS Registry Number 1919888-06-4
NCIT ID C148501


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cyclophosphamide + LY3295668 + Topotecan Cyclophosphamide LY3295668 Topotecan 0 1
LY3295668 LY3295668 1 4
LY3295668 + LY3537982 LY3295668 LY3537982 0 1
LY3295668 + Midazolam LY3295668 Midazolam 0 1
LY3295668 + Osimertinib LY3295668 Osimertinib 0 1

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