Disease Detail


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ID DOID:2893
Name cervix carcinoma
Definition A cervical cancer that is located_in the cervix uteri or located_in the cervical area and that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.
Source DiseaseOntology.org
Alt Ids
Path disease disease of cellular proliferation cancer organ system cancer reproductive organ cancer female reproductive organ cancer cervical cancer cervix carcinoma


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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
BRAF mutant KO-947 cervix carcinoma predicted - sensitive detail...
NRAS mutant KO-947 cervix carcinoma predicted - sensitive detail...
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT01607905 Phase I Selinexor Safety Study of the Selective Inhibitor of Nuclear Export (SINE) KPT-330 in Patients With Advanced or Metastatic Solid Tumor Cancer Completed USA | CAN 1
NCT02164461 Phase Ib/II ADXS11-001 ADXS11-001 High Dose HPV+ Cervical Cancer Completed USA 0
NCT02291055 Phase Ib/II Durvalumab ADXS11-001 Phase 1-2 Study of ADXS11-001 or MEDI4736 Alone or Combo In Cervical or HPV+ Head & Neck Cancer Unknown status USA 0
NCT02315066 Phase I PF-04518600 PF-04518600 + Utomilumab Study Of OX40 Agonist PF-04518600 Alone And In Combination With 4-1BB Agonist PF-05082566 Completed USA | FRA 2
NCT02394652 Phase II Cisplatin Metformin The Potential for Metformin to Improve Tumor Oxygenation in Locally Advanced Cervix Cancer Completed CAN 0
NCT02628067 Phase II Pembrolizumab Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158) Recruiting USA | ITA | FRA | ESP | DEU | CAN 13
NCT02723955 Phase I GSK3359609 GSK3359609 + Pembrolizumab Dose Escalation and Expansion Study of GSK3359609 in Subjects With Selected Advanced Solid Tumors (INDUCE-1) Active, not recruiting USA | ITA | FRA | ESP | CAN 4
NCT02835833 Phase I Bevacizumab + Nintedanib Study of Nintedanib Plus Bevacizumab in Advanced Solid Tumors Completed USA 0
NCT02921269 Phase II Atezolizumab + Bevacizumab Atezolizumab and Bevacizumab in Treating Patients With Recurrent, Persistent, or Metastatic Cervical Cancer Completed USA 0
NCT03192059 Phase II Aspirin + Cyclophosphamide + Pembrolizumab + Vitamin D Study of Pembrolizumab, Radiation and Immune Modulatory Cocktail in Cervical/Uterine Cancer (PRIMMO) Completed BEL 0
NCT03345784 Phase I Adavosertib + Cisplatin WEE1 Inhibitor AZD1775, External Beam Radiation Therapy, and Cisplatin in Treating Patients With Cervical, Vaginal, or Uterine Cancer Active, not recruiting USA | CAN 0
NCT03418480 Phase Ib/II BNT113 HPV Anti-CD40 RNA Vaccine (HARE-40) Recruiting 1
NCT03476798 Phase II Bevacizumab + Rucaparib Bevacizumab and Rucaparib in Recurrent Carcinoma of the Cervix or Endometrium Active, not recruiting USA 0
NCT03752398 Phase I Izuralimab A Study of XmAb23104 in Subjects With Selected Advanced Solid Tumors (DUET-3) (DUET-3) Recruiting USA 0
NCT03849469 Phase I Pembrolizumab + XmAb22841 XmAb22841 A Study of XmAb22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tumors (DUET-4) Active, not recruiting USA 0
NCT04483544 Phase II Olaparib + Pembrolizumab Pembrolizumab and Olaparib in Cervical Cancer Patients Recruiting USA 0
NCT04487587 Phase II Cediranib + Olaparib A Phase II Clinical Trial of Cediranib and Olaparib Maintenance in Advanced Recurrent Cervical Cancer (COMICE) Unknown status 1
NCT04925284 Phase I XB002 Nivolumab + XB002 Study of XB002 in Subjects With Solid Tumors (JEWEL-101) Recruiting USA 0
NCT05032040 Phase II XmAb20717 A Study of XmAb20717 in Patients With Selected Advanced Gynecologic and Genitourinary Malignancies Recruiting USA 0
NCT05063916 Phase II AK104 Phase II Study of AK104 (Cadonilimab) for Recurrent Small Cell Neuroendocrine Carcinomas of the Cervix Recruiting USA 0
NCT05325866 Phase I Bemarituzumab A Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression (FORTITUDE-301) Recruiting USA | FRA | ESP | CAN | BEL | AUT 11