Disease Detail

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
FGFR1 amp AZD4547 lung large cell carcinoma sensitive detail...
FGFR1 positive AZD4547 + AZD8055 lung large cell carcinoma sensitive detail...
FGFR1 positive AZD4547 + Vistusertib lung large cell carcinoma sensitive detail...
FGFR1 positive AZD4547 + Sirolimus lung large cell carcinoma sensitive detail...
TP53 R175L NSC319726 lung large cell carcinoma sensitive detail...
TP53 wild-type NSC319726 lung large cell carcinoma resistant detail...
FGFR1 amp ODM-203 lung large cell carcinoma sensitive detail...
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02185690 Phase I Binimetinib + Carboplatin + Pemetrexed Disodium A Phase I/Ib Study of MEK162, a MEK Inhibitor, in Combination With Carboplatin and Pemetrexed in Patients With Non-squamous Carcinoma of the Lung Completed CAN 0
NCT03591731 Phase II Nivolumab Ipilimumab + Nivolumab Nivolumab +/- Ipilimumab in Patients With Advanced, Refractory Pulmonary or Gastroenteropancreatic Poorly Differentiated Neuroendocrine Tumors (NECs) (NIPINEC) Active, not recruiting FRA 0
NCT03976518 Phase II Atezolizumab Atezolizumab in Advanced Non-small Cell Lung Cancer With Rare Histologies (CHANCE Trial) (CHANCE) Recruiting ITA 0
NCT04748419 Phase Ib/II Durvalumab Safety and Efficacy of Consolidative Hypofractionated Radiation Therapy (hfRT) for Boosting the Residual Primary Lung Cancer With Durvalumab Recruiting USA 0
NCT05198830 Phase II Cisplatin + Durvalumab + Pemetrexed Disodium Cisplatin + Durvalumab + Pemetrexed Disodium + TRC102 Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung Cancer Recruiting USA 0