Disease Detail

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
PIK3CA H1047X Bortezomib + Temsirolimus + Topotecan small intestine adenocarcinoma predicted - resistant detail...
MLH1 mutant N/A small intestine adenocarcinoma not applicable detail...
MSH6 mutant N/A small intestine adenocarcinoma not applicable detail...
STK11 mutant N/A small intestine adenocarcinoma sensitive detail...
APC mutant N/A small intestine adenocarcinoma not applicable detail...
Clinical Trial Phase Therapies Title Recruitment Status
NCT01202409 Phase II Panitumumab CAPOX in KRAS Wild-Type Advanced Adenocarcinoma of the Small Bowel or Ampulla of Vater Completed
NCT01208103 Phase II Bevacizumab + Capecitabine + Oxaliplatin Bevacizumab With Capecitabine and Oxaliplatin in Advanced Adenocarcinoma of the Small Bowel or Ampulla of Vater Completed
NCT02034110 Phase II Dabrafenib + Trametinib Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib in Subjects With BRAF V600E- Mutated Rare Cancers Active, not recruiting
NCT02834013 Phase 0 Ipilimumab + Nivolumab Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting
NCT03000179 Phase II Avelumab Safety and Efficacy of Avelumab in Small Intestinal Adenocarcinoma Active, not recruiting
NCT03095781 Phase I Pembrolizumab + XL888 Pembrolizumab and XL888 in Patients With Advanced Gastrointestinal Cancer Recruiting
NCT03108131 Phase II Atezolizumab + Cobimetinib Cobimetinib and Atezolizumab in Advanced Rare Tumors Recruiting
NCT03597581 Phase I RGX202 Fluorouracil + Irinotecan + Leucovorin + RGX202 A Study of RGX-202-01 With or Without FOLFIRI in Patients With Advanced Gastrointestinal Malignancies Recruiting