Disease Detail

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
FBXW7 R465H MRK-003 T-cell adult acute lymphocytic leukemia resistant detail...
FBXW7 del MRK-003 T-cell adult acute lymphocytic leukemia resistant detail...
FBXW7 R505C MRK-003 T-cell adult acute lymphocytic leukemia resistant detail...
FBXW7 R479Q MRK-003 T-cell adult acute lymphocytic leukemia resistant detail...
FBXW7 R465C MRK-003 T-cell adult acute lymphocytic leukemia resistant detail...
FBXW7 R505L MRK-003 T-cell adult acute lymphocytic leukemia resistant detail...
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT01363817 Phase I Dexamethasone BMS-906024 Study to Evaluate the Safety and Tolerability of Weekly Intravenous (IV) Doses of BMS-906024 in Subjects With Acute T-cell Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma Completed USA | FRA | DEU 0
NCT02763384 Phase II BKT140 + Nelarabine BL-8040 and Nelarabine for Relapsed or Refractory T-Acute Lymphoblastic Leukemia/ Lymphoblastic Lymphoma Terminated USA 0
NCT02999633 Phase II Isatuximab Safety and Efficacy of Isatuximab in Lymphoblastic Leukemia (ISLAY) Terminated USA | ITA | FRA 4
NCT05519527 Phase I STI-6129 A Phase 1, Open-Label, Dose-Escalation Study of Safety And Efficacy of An Anti-CD38 Antibody Drug Conjugate (STI-6129) In Patients With Relapsed Or Refractory T-Acute Lymphoblastic Leukemia/Lymphoma (T-ALL) Or Acute Myeloid Leukemia (AML) Withdrawn 0