Disease Detail

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
PDGFRA amp Imatinib malignant peripheral nerve sheath tumor sensitive detail...
Unknown unknown Dasatinib malignant peripheral nerve sheath tumor not applicable detail...
Unknown unknown Everolimus malignant peripheral nerve sheath tumor not applicable detail...
Unknown unknown Alisertib malignant peripheral nerve sheath tumor not applicable detail...
Unknown unknown Carfilzomib + Selinexor malignant peripheral nerve sheath tumor not applicable detail...
Clinical Trial Phase Therapies Title Recruitment Status
NCT02301039 Phase II Pembrolizumab A Phase II Study of the Anti-PD1 Antibody Pembrolizumab (MK-3475) in Patients With Advanced Sarcomas Active, not recruiting
NCT02584309 Phase II dexrazoxane Doxorubicin + Olaratumab Doxorubicin With Upfront Dexrazoxane Plus Olaratumab for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma Recruiting
NCT02584647 Phase Ib/II Pexidartinib + Sirolimus Combination of PLX3397 and Sirolimus in Unresectable Sarcoma (Phase 1) and Malignant Peripheral Nerve Sheath Tumors (Phase 2) Recruiting
NCT02601209 Phase Ib/II Pazopanib Sapanisertib Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma Active, not recruiting
NCT02978859 Phase II MGCD516 MGCD516 in Advanced Liposarcoma and Other Soft Tissue Sarcomas Recruiting
NCT02986919 Phase II CPI-0610 Study of CPI-0610 in Patients With Malignant Peripheral Nerve Sheath Tumors Withdrawn
NCT02987959 Phase II Sapanisertib Study of TAK-228 (MLN0128) in Soft Tissue Sarcomas Recruiting
NCT03009201 Phase I Doxorubicin + Ribociclib Ribociclib and Doxorubicin Hydrochloride in Treating Patients Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery Recruiting