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Drug Name AEB071
Trade Name
Synonyms Sotrastaurin
Drug Descriptions

Sotrastaurin (AEB071) is a pan-PKC inhibitor, which induces cell cycle arrest and apoptosis (PMID: 19491325).

DrugClasses PKC Inhibitor (Pan) 10

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AEB071 AEB071 3 2
AEB071 + Alpelisib AEB071 Alpelisib 0 1
AEB071 + Binimetinib AEB071 Binimetinib 3 1
AEB071 + CGM097 AEB071 CGM097 2 0
AEB071 + Everolimus AEB071 Everolimus 2 1
AEB071 + PD-0325901 AEB071 PD-0325901 1 0


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