Drug Detail


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Drug Name PQR309
Trade Name
Synonyms PQR 309|PQR-309|Bimiralisib
Drug Descriptions

PQR309 (Bimiralisib) is a dual pan-PI3K and mTORC1/2 inhibitor, which blocks PI3K/mTOR signaling, potentially resulting in inhibition of tumor growth (PMID: 29066507).

DrugClasses mTOR Inhibitor 51 PI3K Inhibitor (Pan) 38
CAS Registry Number 1225037-39-7
NCIT ID C111898


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Ibrutinib + PQR309 Ibrutinib PQR309 1 0
Panobinostat + PQR309 PQR309 Panobinostat 1 0
PQR309 PQR309 2 4
PQR309 + Rituximab PQR309 Rituximab 1 0
PQR309 + Venetoclax PQR309 Venetoclax 1 0

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