Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Tamatinib
Trade Name
Synonyms R406|R-406
Drug Descriptions

Tamatinib (R406) inhibits SYK, resulting in decreased downstream signaling and and potentially leading to reduced tumor cell proliferation and viability (PMID: 16946104, PMID: 26251761, PMID: 30668583).

DrugClasses SYK Inhibitor 15
CAS Registry Number 841290-80-0


  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")


  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
A-770041 + Tamatinib A-770041 Tamatinib 0 0
Pictilisib + Tamatinib Pictilisib Tamatinib 0 0
Tamatinib Tamatinib 5 0
Tamatinib + Tazemetostat Tamatinib Tazemetostat 0 0
Tamatinib + Trametinib Tamatinib Trametinib 0 0

Additional content available in CKB BOOST