Disease Detail


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ID DOID:80374
Name gastroesophageal cancer
Definition A gastrointestinal system cancer that is located_in the proximal esophagus and the distal stomach.
Source DiseaseOntology.org
Alt Ids
Path disease disease of cellular proliferation cancer organ system cancer gastrointestinal system cancer gastroesophageal cancer


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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
Unknown unknown Emibetuzumab + Ramucirumab gastroesophageal cancer not applicable detail...
ARID1A mutant unspecified PD-1 antibody gastroesophageal cancer predicted - sensitive detail...
ARID1A mutant unspecified PD-L1 antibody gastroesophageal cancer predicted - sensitive detail...
ERBB2 positive Margetuximab + Pembrolizumab gastroesophageal cancer predicted - sensitive detail...
Unknown unknown Ganetespib gastroesophageal cancer not applicable detail...
Clinical Trial Phase Therapies Title Recruitment Status
NCT02795156 Phase II Cabozantinib Afatinib Regorafenib Study Assessing Activity of Molecularly Matched Targeted Therapies in Select Tumor Types Based on Genomic Alterations Recruiting
NCT03628677 Phase I AB154 AB154 + GLS-010 A Study to Evaluate the Safety and Tolerability of AB154 in Participants With Advanced Malignancies Recruiting
NCT03694249 Phase II Ifetroban sodium Ifetroban in Treating Patients With Malignant Solid Tumors at High Risk of Metastatic Recurrence Recruiting
NCT03775850 Phase Ib/II EDP1503 EDP1503 + Pembrolizumab A Study of EDP1503 in Patients With Colorectal Cancer, Breast Cancer, and Checkpoint Inhibitor Relapsed Tumors Recruiting
NCT03798626 Phase I Bevacizumab + Fluorouracil + Leucovorin + Oxaliplatin + XOMA 052 Paclitaxel + Ramucirumab + XOMA 052 Bevacizumab + Fluorouracil + Irinotecan + Leucovorin + XOMA 052 Cabozantinib + XOMA 052 Gevokizumab With Standard of Care Anti-cancer Therapies for Metastatic Colorectal, Gastroesophageal, and Renal Cancers Recruiting
NCT03943004 Phase I DFP-14927 Trial of DFP-14927 in Advanced Solid Tumors Recruiting
NCT04020185 Phase Ib/II IMSA101 + unspecified PD-L1 antibody IMSA101 + unspecified PD-1 antibody IMSA101 Safety and Efficacy Study of IMSA101 in Refractory Malignancies Recruiting
NCT04074343 Phase I Irinotecan + trifluridine/tipiracil hydrochloride TAS-102 and Irinotecan in 2L+ Gastric and Gastroesophageal Adenocarcinoma Recruiting
NCT04147819 Phase I BAY2701439 A First in Human Study of BAY2701439 to Look at Safety, How the Body Absorbs, Distributes and Excretes the Drug, and How Well the Drug Works in Participants With Advanced Cancer Expressing the HER2 Protein Recruiting
NCT04209686 Phase II Olaparib + Paclitaxel + Pembrolizumab Paclitaxel, Pembrolizumab and Olaparib in Previously Treated Advanced Gastric Adenocarcinoma Recruiting
NCT04225117 Phase II Enfortumab vedotin-ejfv A Study to Evaluate Enfortumab Vedotin in Subjects With Previously Treated Locally Advanced or Metastatic Malignant Solid Tumors (EV-202) Recruiting