Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Rivoceranib
Trade Name
Synonyms YN968D1|Apatinib
Drug Descriptions

Rivoceranib (apatinib) is an inhibitor of receptor tyrosine kinases, including KDR (VEGFR2), RET, c-KIT, Src, and PDGFRa, which may result in reduced cell proliferation and inhibition of tumor growth (PMID: 21443688, PMID: 32669874).

DrugClasses KIT Inhibitor 51 RET Inhibitor 40 SRC Inhibitor 30 VEGFR2 Inhibitor 35
CAS Registry Number 1218779-75-9
NCIT ID C74012


  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"


  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Afatinib + Rivoceranib Afatinib Rivoceranib 0 0
Camrelizumab + Rivoceranib Camrelizumab Rivoceranib 0 0
Camrelizumab + Rivoceranib + SHR9146 Camrelizumab Rivoceranib SHR9146 0 0
Nivolumab + Rivoceranib Nivolumab Rivoceranib 0 1
Pembrolizumab + Rivoceranib Pembrolizumab Rivoceranib 0 1
Pyrotinib + Rivoceranib Pyrotinib Rivoceranib 0 0
Rivoceranib Rivoceranib 0 3
Rivoceranib + Tegafur-gimeracil-oteracil Potassium Rivoceranib Tegafur-gimeracil-oteracil Potassium 0 0
Rivoceranib + Trifluridine-tipiracil hydrochloride Rivoceranib Trifluridine-tipiracil hydrochloride 0 1

Additional content available in CKB BOOST