Drug Detail


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Drug Name H3B-5942
Trade Name
Synonyms CS-0047696
Drug Descriptions

H3B-5942 is a selective estrogen receptor covalent antagonist, which antagonizes wild-type and mutant forms of estrogen receptor alpha, potentially resulting in decreased tumor cell proliferation and reduced tumor growth (PMID: 29991605).

DrugClasses Hormone - Anti-estrogens 25
CAS Registry Number 2052128-15-9


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abemaciclib + H3B-5942 Abemaciclib H3B-5942 0 0
AZD8055 + H3B-5942 AZD8055 H3B-5942 0 0
Everolimus + H3B-5942 Everolimus H3B-5942 0 0
H3B-5942 H3B-5942 0 0
H3B-5942 + Palbociclib H3B-5942 Palbociclib 0 0
H3B-5942 + PF-04691502 H3B-5942 PF-04691502 0 0
H3B-5942 + PKI-402 H3B-5942 PKI-402 0 0
H3B-5942 + Ribociclib H3B-5942 Ribociclib 0 0
H3B-5942 + Sirolimus H3B-5942 Sirolimus 0 0
H3B-5942 + Temsirolimus H3B-5942 Temsirolimus 0 0

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