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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
Unknown unknown Nelfinavir + Radiotherapy rectum cancer not applicable detail...
BRAF V600E Cetuximab rectum cancer resistant detail...
BRAF V600E Panitumumab rectum cancer resistant detail...
NRAS exon2 Cetuximab rectum cancer resistant detail...
NRAS exon2 Panitumumab rectum cancer resistant detail...
NRAS exon4 Cetuximab rectum cancer resistant detail...
NRAS exon4 Panitumumab rectum cancer resistant detail...
NRAS exon3 Cetuximab rectum cancer resistant detail...
NRAS exon3 Panitumumab rectum cancer resistant detail...
BRAF wild-type ERBB2 amp NRAS wild-type Lapatinib + Trastuzumab rectum cancer sensitive detail...
BRAF wild-type ERBB2 amp NRAS wild-type Pertuzumab + Trastuzumab rectum cancer sensitive detail...
MLH1 mutant N/A rectum cancer not applicable detail...
MSH6 mutant N/A rectum cancer not applicable detail...
Clinical Trial Phase Therapies Title Recruitment Status
NCT01274624 Phase I Fluorouracil + Irinotecan + Leucovorin Bevacizumab + Pelareorep Study of REOLYSIN; in Combination With FOLFIRI and Bevacizumab in FOLFIRI Naive Patients With KRAS Mutant Metastatic Colorectal Cancer Completed
NCT01309126 Phase III Cetuximab Cetuximab + PGG beta-glucan Study of Imprime PGG in Combination With Cetuximab in Subjects With Recurrent or Progressive KRAS Wild Type Colorectal Cancer Terminated
NCT01740648 Phase I Fluorouracil + Trametinib Trametinib, Fluorouracil, and Radiation Therapy Before Surgery in Treating Patients With Stage II-III Rectal Cancer Active, not recruiting
NCT01966289 Phase I Cyclophosphamide Guadecitabine GVAX colorectal cancer vaccine SGI-110 in Combination With an Allogeneic Colon Cancer Cell Vaccine (GVAX) and Cyclophosphamide (CY) in Metastatic Colorectal Cancer (mCRC) Active, not recruiting
NCT01985763 Phase Ib/II Genistein Bevacizumab Fluorouracil + Leucovorin + Oxaliplatin + Pembrolizumab Genistein in Treatment of Metastatic Colorectal Cancer Completed
NCT02041481 Phase I Binimetinib + Fluorouracil + Leucovorin + Oxaliplatin MEK Inhibitor MEK162 in Combination With Leucovorin Calcium, Fluorouracil, and Oxaliplatin in Treating Patients With Advanced Metastatic Colorectal Cancer Completed
NCT02199236 Phase I Capecitabine + Fluorouracil Dose Escalation Trial of Endoluminal High-Dose-Rate Brachytherapy With Concurrent Chemotherapy for Rectal or Anal Cancer in Patients With Recurrent Disease or Undergoing Non-Operative Management Recruiting
NCT02399813 Phase Ib/II ADXS11-001 Phase 2 Study of ADXS11-001 in Subjects With Anal Cancer or Cancer of the Rectum Completed
NCT02508077 Phase II Fluorouracil + Irinotecan + Leucovorin Panitumumab FOLFIRI and Panitumumab in Treating Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer Terminated
NCT02890758 Phase I ALT-803 Phase I Trial of Universal Donor NK Cell Therapy in Combination With ALT803 Recruiting
NCT03127098 Phase Ib/II ALT-803 + ETBX-011 QUILT-3.040: ETBX-011 (Ad5 [E1-, E2b-]-CEA(6D)) Vaccine in Combination With ALT-803 (Super-agonist IL-15) in Subjects Having CEA-Expressing Cancer Completed
NCT03152370 Phase I E7046 + Fluorouracil + Leucovorin + Oxaliplatin Capecitabine + E7046 Preoperative Radiotherapy and E7046 in Rectum Cancer (PRAER 1) Active, not recruiting
NCT03317119 Phase I Trametinib + trifluridine/tipiracil hydrochloride Trametinib and Trifluridine and Tipiracil Hydrochloride in Treating Patients With Colon or Rectal Cancer That is Advanced, Metastatic, or Cannot Be Removed by Surgery Active, not recruiting
NCT03516708 Phase Ib/II Pembrolizumab Epacadostat Capecitabine + Oxaliplatin Epacadostat (INCB024360) and Pembrolizumab Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer Recruiting
NCT03770689 Phase Ib/II Capecitabine Capecitabine + MSC2490484A Phase Ib/II Study of M3814 in Combination With Capecitabine and Radiotherapy in Rectal Cancer Recruiting
NCT03829410 Phase Ib/II Bevacizumab + Fluorouracil + Irinotecan + Leucovorin + Onvansertib Onvansertib in Combination With FOLFIRI and Bevacizumab for Second Line Treatment of Metastatic Colorectal Cancer Patients With a Kras Mutation Recruiting